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Seattle is in first place in the Western Conference and is the betting favorite facing a reeling Colorado squad that has lost five straight matches. However, there are some key matches this weekend that have playoff implications.

One of the bigger weekend matches in the in the Western Conference with the 5th place side Vancouver Whitecaps playing host to 6th place side Portland Timbers. The Whitecaps are the betting favorite and can really improve their playoff position, and hurt Portland’s, with a win.

Neither team is in top form with the Whitecaps only having one win in their last five matches while the Timbers only have two.

Bet365 has Vancouver as the MLS betting favorite at +100 with Portland at +260 and a draw line of +250.

DC United is in first place in the Eastern Conference and they are playing host to a New York Red Bulls squad that is fighting to stay in the playoff race. New York only has one loss in their last five matches and they are only one point ahead of Philadelphia and New England for the last playoff spot in the East.

DC United is coming off a loss, but at home they are the betting favorite at Bet365 with odds of +120 and New York at +225 and a draw line of +230.

The Chicago Fire are in desperate need of a W, being five points back of New York in the East, but while they are favorites in their upcoming match they face a Dallas squad that is on a four-match winning streak.

Bet365 has MLS betting odds for this match with Chicago at +130 and Dallas at +188 with a draw line at +250.

Chicago has conceded six more goals this season then they have scored, which does not bode well facing Dallas, who has scored the most goals in the MLS this season.

With Sporting Kansas City not in top form they have fallen from the top spot in the East and now only have the third best betting odds to win the MLS Cup. Big surprise that Seattle has the best betting odds at +550 followed by DC United (+600) and LA (+600) with Kansas City at +700. Sporting KC has two losses in their last three matches.